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1

SPIE Proceedings [SPIE Microlithography 2000 - Santa Clara, CA (Sunday 27 February 2000)] Advances in Resist Technology and Processing XVII - Epoxidized novolac resist (EPR) for high-resolution negative- and positive-tone electron beam lithography

Tegou, Evangelia, Gogolides, Evangelos, Argitis, Panagiotis, Raptis, Ioannis, Patsis, George P., Glezos, Nikos, Tan, Zoilo C. H., Lee, Kim Y., Le, Phuong T., Hsu, Yautzong, Hatzakis, Michael, Houlihan

Année:

2000

Langue:

english

Fichier:

PDF, 709 KB

english, 2000

2

Changes in T Cell Receptor Excision DNA Circle (TREC) Levels in HIV Type 1-Infected Subjects Pre- and Post-Highly Active Antiretroviral Therapy

Touloumi, Giota, Pantazis, Nikos, Karafoulidou, Anastasia, Mandalaki, Titika, Goedert, James J., Kostrikis, Leondios G., Hatzakis, Angelos

Journal:

AIDS Research and Human Retroviruses

Année:

2004

Langue:

english

Fichier:

PDF, 197 KB

english, 2004

3

Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity

Stella, Stefano, Mesa, Pablo, Thomsen, Johannes, Paul, Bijoya, Alcón, Pablo, Jensen, Simon B., Saligram, Bhargav, Moses, Matias E., Hatzakis, Nikos S., Montoya, Guillermo

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 11.49 MB

english, 2018

4

Single Liposome Measurements for the Study of Proton-Pumping Membrane Enzymes Using Electrochemistry and Fluorescent Microscopy

Mazurenko, Ievgen, Hatzakis, Nikos S., Jeuken, Lars J.C.

Journal:

Journal of Visualized Experiments

Année:

2019

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2019

5

Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition

Bohr, Søren S.-R., Lund, Philip M., Kallenbach, Amalie S., Pinholt, Henrik, Thomsen, Johannes, Iversen, Lars, Svendsen, Allan, Christensen, Sune M., Hatzakis, Nikos S.

Journal:

Scientific Reports

Année:

2019

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2019

6

Positional Assembly of Enzymes in Polymersome Nanoreactors for Cascade Reactions

Dennis M. Vriezema, Paula M. L. Garcia, Núria Sancho Oltra, Nikos S. Hatzakis, Suzanne M. Kuiper, Roeland J. M. Nolte, Alan E. Rowan, Jan C. M. van Hest

Journal:

Angewandte Chemie

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

7

Positional Assembly of Enzymes in Polymersome Nanoreactors for Cascade Reactions

Dennis M. Vriezema, Paula M. L. Garcia, Núria Sancho Oltra, Nikos S. Hatzakis, Suzanne M. Kuiper, Roeland J. M. Nolte, Alan E. Rowan, Jan C. M. van Hest

Journal:

Angewandte Chemie International Edition

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

8

β-Cyclodextrin-Appended Giant Amphiphile: Aggregation to Vesicle Polymersomes and Immobilisation of Enzymes

Marco Felici, María Marzá-Pérez, Nikos S. Hatzakis, Roeland J. M. Nolte, Martin C. Feiters

Journal:

Chemistry - A European Journal

Année:

2008

Langue:

english

Fichier:

PDF, 686 KB

english, 2008

9

Asymmetric transesterification of secondary alcohols catalyzed by feruloyl esterase from Humicola insolens

Nikos S. Hatzakis, Ioulia Smonou

Journal:

Bioorganic Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 180 KB

english, 2005

10

Enantioselectivity and diastereoselectivity in the transesterification of secondary alcohols mediated by feruloyl esterase from Humicola insolens

Nikos S. Hatzakis, Ioulia Smonou

Journal:

Tetrahedron Letters

Année:

2004

Langue:

english

Fichier:

PDF, 264 KB

english, 2004

11

Oxidation of benzyl alcohols by dimethyldioxirane. The question of concerted versus stepwise mechanisms probed by kinetic isotope effects

Yiannis S Angelis, Nikos S Hatzakis, Ioulia Smonou, Michael Orfanopoulos

Journal:

Tetrahedron Letters

Année:

2001

Langue:

english

Fichier:

PDF, 83 KB

english, 2001

12

How curved membranes recruit amphipathic helices and protein anchoring motifs

Hatzakis, Nikos S, Bhatia, Vikram K, Larsen, Jannik, Madsen, Kenneth L, Bolinger, Pierre-Yves, Kunding, Andreas H, Castillo, John, Gether, Ulrik, Hedegård, Per, Stamou, Dimitrios

Journal:

Nature Chemical Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2009

13

Ferulic acid esterase from Humicola Insolens catalyzes enantioselective transesterification of secondary alcohols

Nikos S. Hatzakis, Dimitra Daphnomili, Ioulia Smonou

Journal:

Journal of Molecular Catalysis B: Enzymatic

Année:

2003

Langue:

english

Fichier:

PDF, 51 KB

english, 2003

14

Single Enzyme Studies Reveal the Existence of Discrete Functional States for Monomeric Enzymes and How They Are “Selected” upon Allosteric Regulation

Hatzakis, Nikos S., Wei, Li, Jorgensen, Sune K., Kunding, Andreas H., Bolinger, Pierre-Yves, Ehrlich, Nicky, Makarov, Ivan, Skjot, Michael, Svendsen, Allan, Hedegård, Per, Stamou, Dimitrios

Journal:

Journal of the American Chemical Society

Année:

2012

Langue:

english

Fichier:

PDF, 394 KB

english, 2012

15

Synthesis and single enzyme activity of a clicked lipase?BSA hetero-dimer

Hatzakis, Nikos S., Engelkamp, Hans, Velonia, Kelly, Hofkens, Johan, Christianen, Peter C. M., Svendsen, Allan, Patkar, Shamkantr A., Vind, Jesper, Maan, Jan C., Rowan, Alan E., Nolte, Roeland J. M.

Journal:

Chemical Communications

Année:

2006

Langue:

english

Fichier:

PDF, 325 KB

english, 2006

16

A unifying mechanism accounts for sensing of membrane curvature by BAR domains, amphipathic helices and membrane-anchored proteins

Vikram Kjøller Bhatia, Nikos S. Hatzakis, Dimitrios Stamou

Journal:

Seminars in Cell & Developmental Biology

Année:

2010

Langue:

english

Fichier:

PDF, 869 KB

english, 2010

17

Mixing subattolitre volumes in a quantitative and highly parallel manner with soft matter nanofluidics

Christensen, Sune M., Bolinger, Pierre-Yves, Hatzakis, Nikos S., Mortensen, Michael W., Stamou, Dimitrios

Journal:

Nature Nanotechnology

Année:

2011

Langue:

english

Fichier:

PDF, 4.61 MB

english, 2011

18

Manipulating The Environment Of a Single Lipase Molecule

Wei, Li, Hatzakis, Nikos, Jørgensen, Sune K., Hedegård, Per, Stamou, Dimitrios

Journal:

Biophysical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 76 KB

english, 2009

19

Influence of Lipid Heterogeneity and Phase Behavior on Phospholipase A2 Action at the Single Molecule Level

Gudmand, Martin, Rocha, Susana, Hatzakis, Nikos S., Peneva, Kalina, Müllen, Klaus, Stamou, Dimitrios, Uji-I, Hiroshi, Hofkens, Johan, Bjørnholm, Thomas, Heimburg, Thomas

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2010

20

Static and Dynamic Disorder Observed in the Phase Transition Behavior of Individual Small Unilamellar Vesicles

Stamou, Dimitrios G., Bendix, Poul Martin, Wibroe, Peter P., Hatzakis, Nikos S.

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 35 KB

english, 2011

21

Synergy of Liquid Ordered “Raft Like” Domains and Membrane Curvature in Promoting Sorting of Lipidated Proteins Such As NRas

Hatzakis, Nikos S., Larsen, Jannik K., Jensen, Martin B., Bhatia, Vikram K., Pedersen, Soren L., Jensen, Knud J., Stamou, Dimitrios

Journal:

Biophysical Journal

Année:

2012

Langue:

english

Fichier:

PDF, 51 KB

english, 2012

22

Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3 + 2] dipolar cycloaddition reaction

Dirks, A. J. (Ton), van Berkel, Sander S., Hatzakis, Nikos S., Opsteen, Joost A., van Delft, Floris L., Cornelissen, Jeroen J. L. M., Rowan, Alan E., van Hest, Jan C. M., Rutjes, Floris P. J. T., Nolt

Journal:

Chemical Communications

Année:

2005

Langue:

english

Fichier:

PDF, 336 KB

english, 2005

23

Single molecule insights on conformational selection and induced fit mechanism

Hatzakis, Nikos S.

Journal:

Biophysical Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 5.56 MB

english, 2014

24

Single Molecule Activity Measurements of Cytochrome P450 Oxidoreductase Reveal the Existence of Two Discrete Functional States

Laursen, Tomas, Singha, Aparajita, Rantzau, Nicolai, Tutkus, Marijonas, Borch, Jonas, Hedegård, Per, Stamou, Dimitrios, Møller, Birger Lindberg, Hatzakis, Nikos S.

Journal:

ACS Chemical Biology

Année:

2014

Langue:

english

Fichier:

PDF, 5.10 MB

english, 2014

25

Bionanoconjugation via Click Chemistry: The Creation of Functional Hybrids of Lipases and Gold Nanoparticles

Brennan, Jennifer L., Hatzakis, Nikos S., Tshikhudo, T. Robert, Razumas, Valdemaras, Patkar, Shamkant, Vind, Jesper, Svendsen, Allan, Nolte, Roeland J. M., Rowan, Alan E., Brust, Mathias

Journal:

Bioconjugate Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 105 KB

english, 2006

26

Single Enzyme Studies Reveal the Existence of Discrete Functional States for Monomeric Enzymes and How they are “Selected” upon Allosteric Regulation

Hatzakis, Nikos S., Wei, Li, Jorgensen, Sune K., Kunding, Andreas H., Bolinger, Pierre-Yves, Ehrlich, Nicky, Makarov, Ivan, Skjot, Michael, Svendsen, Allan, Hedegård, Per, Walsh, Samuel M., Stamou, Di

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 53 KB

english, 2013

27

How Membrane Curvature Drives the Up-Concentration of N-Ras Proteins to Ordered Lipid Domains : Correlation of In Vivo and In Vitro Experiments with Mean Field Theory Calculations and Coarse Grain Simulations

Hatzakis, Nikos S., Larsen, Jannik, Jensen, Martin B., Bhatia, Vikram K., Pedersen, Søren L., Koldsoe, Heidi, Fowler, Philip, Uline, Mark J., Szleifer, Igal G., Bjornholm, Thomas, Sansom, Mark, Jensen

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 103 KB

english, 2014

28

Lipid-Anchored Ras is Sorted by Membrane Curvature Both In Vitro and in Living Cells

Larsen, Jannik, Jensen, Martin B., Bhatia, Vikram K., Pedersen, Søren L., Bjørnholm, Thomas, Jensen, Knud J., Kohnke, Monika, Abankwa, Daniel, Alexandrov, Kirill, Hatzakis, Nikos S., Stamou, Dimitrios

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 43 KB

english, 2013

29

Regulation of Enzymatic Activity Occurs by Selection of Discrete Activity States

Hatzakis, Nikos S., Wei, Li, Jorgensen, Sune K., Kunding, Andreas H., Hedegard, Per, Stamou, Dimitrios

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 33 KB

english, 2011

30

Soft Matter Based Nanofluidic Platform for Highly Parallel Mixing of Sub-Attoliter Total Volumes

Christensen, Sune, Bolinger, Pierre-Yves, Hatzakis, Nikos S., Mortensen, Michael W., Stamou, Dimitrios

Journal:

Biophysical Journal

Année:

2012

Langue:

english

Fichier:

PDF, 66 KB

english, 2012

31

Sorting of tN-Ras by Membrane Curvature in Lipid Vesicles and Tubes

Rosholm, Kadla R., Larsen, Jannik, Pedersen, Søren L., Munch, Henrik K., Jensen, Knud J., Hatzakis, Nikos, Stamou, Dimitrios

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 35 KB

english, 2013

32

Observation of Inhomogeneity in the Lipid Composition of Individual Nanoscale Liposomes

Larsen, Jannik, Hatzakis, Nikos S., Elizondo, Elisa, Cabrera, Ingrid, Veciana, Jaume, Ventosa, Nora, Stamou, Dimitrios

Journal:

Biophysical Journal

Année:

2012

Langue:

english

Fichier:

PDF, 38 KB

english, 2012

33

Creating a Proteoliposome Assay for Single Photosystem I Activity Assessment

Jørgensen, Sune K., Lassen, Lærke M.M., Kemmer, Gerdi, Gunther-Pomorski, Thomas, Stamou, Dimitrios, Bjørnholm, Thomas, Jensen, Poul E., Hatzakis, Nikos S.

Journal:

Biophysical Journal

Année:

2012

Langue:

english

Fichier:

PDF, 55 KB

english, 2012

34

Single Proton Pump Activity Measurements on Single Vesicles for a Quinol Heme-Copper Oxidase

Jorgensen, Sune K., McMillan, Duncan, Krzeminski, Lukasz, Stamou, Dimitrios, Jeuken, Lars J.C., Hatzakis, Nikos S.

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 53 KB

english, 2013

35

Developing an Assay to Probe Activtion and Conformational Dynamics of β2-Adrenergic Receptor on Single Molecule Level

Veshaguri, Salome, Tutkus, Marijonas, Lundgaard, Christian V., Tønnesen, Asger, Mathiasen, Signe, Jørgensen, Sune K., Iversen, Lars, Hatzakis, Nikos S., Rasmussen, Søren G., Stamou, Dimitrios

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 37 KB

english, 2013

36

Influence of the Preparation Route on the Supramolecular Organization of Lipids in a Vesicular System

Elizondo, Elisa, Larsen, Jannik, Hatzakis, Nikos S., Cabrera, Ingrid, Bjørnholm, Thomas, Veciana, Jaume, Stamou, Dimitrios, Ventosa, Nora

Journal:

Journal of the American Chemical Society

Année:

2012

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2012

37

Observation of Inhomogeneity in the Lipid Composition of Individual Nanoscale Liposomes

Larsen, Jannik, Hatzakis, Nikos S., Stamou, Dimitrios

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2011

38

Optically Induced Linking of Protein and Nanoparticles to Gold Surfaces

Moth-Poulsen, Kasper, Kofod-Hansen, Vesna, Kamounah, Fadhil S., Hatzakis, Nikos S., Stamou, Dimitrios, Schaumburg, Kjeld, Christensen, Jørn B.

Journal:

Bioconjugate Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2010

39

Do enzymes sleep and work?

Engelkamp, Hans, Hatzakis, Nikos S., Hofkens, Johan, De Schryver, Frans C., Nolte, Roeland J. M., Rowan, Alan E.

Journal:

Chemical Communications

Année:

2006

Langue:

english

Fichier:

PDF, 516 KB

english, 2006

40

INSIGHTS IN ENZYME FUNCTIONAL DYNAMICS AND ACTIVITY REGULATION BY SINGLE MOLECULE STUDIES

JØRGENSEN, SUNE K., HATZAKIS, NIKOS S.

Journal:

Biophysical Reviews and Letters

Année:

2013

Langue:

english

Fichier:

PDF, 444 KB

english, 2013

41

Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases

Larsen, Jannik Bruun, Jensen, Martin Borch, Bhatia, Vikram K, Pedersen, Søren L, Bjørnholm, Thomas, Iversen, Lars, Uline, Mark, Szleifer, Igal, Jensen, Knud J, Hatzakis, Nikos S, Stamou, Dimitrios

Journal:

Nature Chemical Biology

Année:

2015

Langue:

english

Fichier:

PDF, 624 KB

english, 2015

42

Monitoring Shifts in the Conformation Equilibrium of the Membrane Protein Cytochrome P450 Reductase (POR) in Nanodiscs

Wadsäter, Maria, Laursen, Tomas, Singha, Aparajita, Hatzakis, Nikos S., Stamou, Dimitrios, Barker, Robert, Mortensen, Kell, Feidenhans'l, Robert, Møller, Birger Lindberg, Cárdenas, Marité

Journal:

Journal of Biological Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2012

43

Single enzyme experiments reveal a long-lifetime proton leak state in a heme-copper oxidase

Li, Mengqiu, Jørgensen, Sune K., McMillan, Duncan G. G., Krzemiński, Łukasz, Daskalakis, Nikolaos N., Partanen, Riitta H., Tutkus, Marijonas, Tuma, Roman, Stamou, Dimitrios, Hatzakis, Nikos S., Jeuken

Journal:

Journal of the American Chemical Society

Année:

2015

Langue:

english

Fichier:

PDF, 2.29 MB

english, 2015

44

Links of Conformational Sampling to Functional Plasticity and Clinical Phenotypes by Single Molecule Studies

Moses, Matias E., Thodberg, Sara, Bavishi, Krutika, Eiersholt, Stine, Li, Darui, Stamou, Dimitrios, Moller, Birger L., Laursen, Tomas, Hatzakis, Nikos S.

Journal:

Biophysical Journal

Année:

2016

Langue:

english

Fichier:

PDF, 41 KB

english, 2016

45

N-RAS Lipid Anchor Adsorption to Membranes as a Function of Lipid Composition and Curvature

Larsen, Jannik B., Kennard, Celeste, Pedersen, Søren L., Jensen, Knud J., Hatzakis, Nikos S., Uline, Mark J., Stamou, Dimitrios

Journal:

Biophysical Journal

Année:

2016

Langue:

english

Fichier:

PDF, 42 KB

english, 2016

46

Cellular HIV-1 DNA load predicts HIV-RNA rebound and the outcome of highly active antiretroviral therapy

Hatzakis, Angelos E, Touloumi, Giota, Pantazis, Nikos, Anastassopoulou, Cleo G, Katsarou, Olga, Karafoulidou, Anastasia, Goedert, James J, Kostrikis, Leondios G

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 111 KB

english, 2004

47

Membrane Curvature Regulates the Localization of G Protein Coupled Receptors and Ras Isoforms

Stamou, Dimitrios, Rosholm, Kadla, Damalas, Alexander, Hatzakis, Nikos, Wirth, Volker, Martinez, Karen, Leijnse, Natascha, Oddershede, Lene, Bendix, Poul Martin, Pedersen, Soren

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 58 KB

english, 2015

48

Single Molecule Activity Measurements of Cytochrome P450 Oxidoreductase Reveal the Existence of Two Discrete Functional States

Laursen, Tomas, Singha, Aparajita, Rantzau, Nicolai, Tutkus, Marijonas, Borch, Jonas, Hedegård, Per, Stamou, Dimitrios, Møller, Birger L., Hatzakis, Nikos S.

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 62 KB

english, 2015

49

Differences in HIV RNA levels before the initiation of antiretroviral therapy among 1864 individuals with known HIV-1 seroconversion dates

Touloumi, Giota, Pantazis, Nikos, Babiker, Abdel G, Walker, Sarah A, Katsarou, Olga, Karafoulidou, Anastasia, Hatzakis, Angelos, Porter, Kholoud

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 126 KB

english, 2004

50

Pneumoconiosis among Cretan Dental Technicians

Froudarakis, Marios E., Voloudaki, Argyro, Bouros, Demosthenes, Drakonakis, George, Hatzakis, Kostas, Siafakas, Nikos M.

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 249 KB

english, 1999